Pharmaceutics-1 1st Semester Unit 2 Most Important MCQs

Pharmaceutics-1 1st Semester Unit 2 Most Important MCQs

Pharmaceutics-1 1st Semester Unit 2 Most Important MCQs

Multiple Choice Questions

1.’Mottling’ is the manufacturing defect associated with:
a. Capsules
c. Tablets
b. Ointments
d. Liniments

2.Which of the following is NOT a solid dosage form?
a. Tablet
b. Capsule
c. Cream
d. Powder

3.Which of the following statement regarding enteric coated tablet is NOT true?
a. Should not be crushed
b. Should not be taken with antacids
c. Should not be swallowed whole
d. None of the above

4.A paracetamol formulation consists of starch and magnesium stearate as additive. A person taking above formulation developed hypersensitivity reaction. It can be due to which of the following?
a. Paracetamol
b. Starch
c. Magnesium stearate
d. All of the above

5.In a patient who is experiencing vomiting, which of the following dosage forms of promethazine would be best?
a. Tablet
b. Syrup
c. Capsule
d. Suppositories

6.The blood of a reckless driver contains 0.1% alcohol. Express the concentration of alcohol in parts per million.
a. 100 ppm
b. 1000 ppm
c. 1 ppm
d. 250 ppm

7.If the adult dose is 60 mg and the age of the child is 4 years, according to Young’s rule the dose for the child will be:
a. 10 mg
b. 15 mg
c. 20 mg
d. 25 mg

8.Hospital formulary provides:
a. General information of drugs which are available in the country
b. Information for procuring, processing, dispensing and administration of drugs in hospital
c. Information of latest adverse drug reactions and regulatory information on drugs
d. None of the above

9.The relative humidity in the operating area of capsule manufacturing is normally:
a. 60%
b. 50%
c. 40%
d. 20%

10.Complete separation of tablet into two or more layers is called as:
a. Capping
b. Lamination
c. Picking
d. Mottling

11.In an ideal suspension, the sedimentation volume should be:
a. Less than 1
b. Zero
c. Equal to 1
d. Between 0 to 1

12.Aspirin is preferably prepared by which method of tablet manufacturing:
a. Direct compression
b. Wet granulation
c. Dry granulation
d. Dry compression and dry granulation

13.Sucking tablets are:
a. For local adsorption
b. Designed to go into the blood stream
c. Both of the above
d. None of the above

14.Rectal suppositories intended for adult use usually weigh approximately:
a. 1g
b. 2g
c. 4g
d. 4 g

15.Weight of rectal suppository for children is:
a. 1g
b. 2g
c. 5 g
d. None

16.Urethral suppositories are also called as:
a. Pessaries
b. Bougies
c. Both
d. None

17.Urethral suppositories have shape:
a. Oviform shape
b. Torpedo shape
c. Pencil shape
d. All

18.Weight of urethral females respectively (in gram):
a. 4 & 2
b. 2 & 4
c. 4 & 6
d. 6 & 4

19.Suppositories are generally evaluated by:
a. Melting range test
b. Breaking test
c. Liquefaction
d. All the above

20.The pH of tears is about:
a. 6.0
b. 8.0
c. 7.4
d. 9.0

21.The appropriate pH range for opthalmic product is:
a. 2.0-3.0
b. 4.0- 6.0
c. 6.0-8.0
d. 8.0-10.0

22.Porosity of a porous powder is defined as:
a. Bulk volume/ Void volume
b. Void volume/ Bulk volume
c. Void volume/ True volume
d. True volume/ Bulk volume

23.A process of separation of molecules through the use of semipermeable membrane is known as:
a. Osmosis
b. Dialysis
c. Sieving
d. None of the above

24.Actuator is a part of aerosol package. It is used to :
a. Dispense the product in desired form
b. Prevent clogging of valve
c. Meter the accurate amount of dose to be dispensed
d. Provide proper attachment of valve to the container

25.Eye drops :
a. Is free from pyrogen
b. Should be sterile and free from foreign particles
c. Should be sterile and pyrogen free
d. All of the above

26.Levigation is defined as:
a. Settling of dispersed solids in suspension
b. Coalescence of dispersed globules in emulsion
c. Micronization of powder by grinding
d. Defect of tablet manufacturing

27.A batch of injectables consisting of 10,000 ampoules each containing 5 ml of the product, the number of ampoules is to be picked up randomly for sterility testing as per IP is:
a. 20 containers
b. 10 containers
c. 2% containers
d. 5%

28. In a friabillator, plastic chamber revolves at:
a. 100 rpm
b. 50 rpm
c. 25 rpm
d. 75 rpm

29.Which of the following equation is used to predict the stability of a drug product at room temperature from experiments at accelerated temperature?
a. Stoke’s equation
b. Michaelis-menten equation
c. Arrhenius equation
d. Young’s equation

30.Melting point of the suppository bases ranges from:
a. 50-60 °C
b. 37-40 °C
c. 20-30 °C
d. 45-50 ° C

31.Enteric coating material for tablet is:
a. Sodium carboxy methyl cellulose
b. Ethyl cellulose
d. Polyvinyl acetate phthalate

32.Diffusivity of a solute is affected by:
b. Pressure
a. Temperature
c. Chemical nature
d. All of the above

33.The mesh size of USP disintegration apparatus is:
a. 2 mesh
b. 5 mesh
c. 10 mesh
d. 20 mesh

34.When one of a solute is soluble in nine parts of a solvent, then the solute is:
a. Very soluble
b. Soluble
c. Sparingly soluble
d. Freely soluble

35.During Norfloxacin tablet coating, your operator complains that there is an irregular distribution of color on the tablet, it is :
a. Capping
b. Chipping
c. Sticking
d. Mottling

36.Seal coating of ranitidine can be done with:
a. Shellac
b. Ethyl cellulose
c. Silicone
d. Any of the above

37.The friability of an uncoated tablet should be:
a. About 1 %
b. Less than 1%
c. More than 1%
d. Set by formulator

38.The content uniformity of a tablet (IP) is necessary when the tablet contents API :
a. Below 50 mg
b. Below 100 mg
c. Below 25 mg
d. Below 10 mg

39.How many milliliters of a 0.9 % aqueous solution can be made from 20 g of sodium chloride?
a. 2222
b. 222
c. 122
d. 100

40.Smallest size of capsule is:
a. 000
b. 1
c. 5
d. 4

41.The shell of capsule is made up of protein which is called:
a. Apalation
b. Gelatin
c. Celatin
d. None

42.Suppositories should be stored in:
a. Cold place
b. Cool place
c. Frozen conditions
d. Not specific

43.SOP is recognized abbreviation for:
a. Student Of Pharmacy
b. Staffing Of Pharmacy
c. Standard Operating Procedure
d. Surgical Operating Parameters

44.The abbreviation UNG means:
a. Eye drops
b. Ointment
c. If necessary
d. Universal dose

45.Sublingual tablets are supposed to take with:
a. Chewing properly.
b. Putting it under the tongue.
c. Putting at the buccal cavity
d. A glass of water

46.Which one of the following is NOT the purpose of coating?
a. Masking the taste
b. Increasing the elegance
c. Increasing efficacy
d. Improving stability

47.Which route of drug administration is most likely to lead to the first pass effect?
a. Sublingual
b. Oral
c. Transdermal
d. Intramuscular

48.Which one of the following is NOT true?
a. To prevent the drug from the influence of external environment
b. To mask bitter tastes
c. To increase friability
d. To make swallowing easier

49.Which of the following is NOT true about suspensions?
a. Some suspensions should contain an antimicrobial agent as a preservative
b. Particle settling could be avoided by using suspending agents
c. Tight containers are necessary to ensure the stability of the final product
d. The suspension should be viscous

50.Which of the following does NOT help to minimize the physical instability of suspensions after their formation?
a. Reducing the particle size of the powders
b. Using thickening agents
c. Using levigating agents
d. Using flavoring agents

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