Pharmaceutics-1 1st Semester Unit 2 Most Important MCQs
Pharmaceutics-1 1st Semester Unit 2 Most Important MCQs
Multiple Choice Questions
1. High concentrations of electrolytes cause the Cracking of soap emulsions by salting out
(A) Emulgent
(B) Suspending agent
(C) Diluent
(D) None of the above
Ans. B) Suspending agent
2. The Commonly used flocculating agent is
(A) Soaps
(B) Sodium benzoate
(C) Tween 80
(D) Bentonite magma
Ans. C) Tween 80
3. Which of the following properties is desirable In a pharmaceutical suspension
I. Caking:
II. Pseudoplastic flow;
III. Thixotropy
(A) I only
(B) III only
(C) II and III only
(D) II and IV only
Ans. C) II and III only
4. Which one is antioxidant
(A) Gallic acid
(B) Mercurials
(C) Benzoic acid derivative
(D) None
Ans. A) Gallic acid
5. A mixture of span 20 and tween 20 forms…..Type of emulsion
(A) W/O
(B) O/W
(C) Milky
(D) Hard
Ans. A) W/O
6. Which one of the following emulsifiers is used To stabilize the emulsion of W/O type
(A) SLS
(B) Span 20
(C) Tween 20
(D) Tragacanth
Ans. B) Span 20
7. A suspension is not a suitable dosage for what Type of injection?
(A) Intra-articular (within the joint)
(B) Intramuscular
(C) Intravenous
(D) Subcutaneous
Ans. C) Intravenous
8. Structured vehicle is included in the Formulation of a suspension to
(A) Prevent the cake formation
(B) Decrease the interfacial, tension
(C) Prevent the sedimentation of particles
(D) None of the above
Ans. B) Decrease the interfacial, tension
9. An emulsifier is considered to be ideal if it is Soluble in
(A) Aqueous phase
(B) oily phase
(C) A & b
(D) None of the above
Ans. C) A & b
10. Creaming in the emulsion can be controlled by Regulating
(A) Density of dispersed phase
(B) Density of dispersion medium
(C) Globule size
(D) Volume of dispersion medium
Ans. C) Globule size
11. Stability of the emulsion is dependent on
(A) Viscosity
(B) Density
(C) Particles Size
(D) All of the above
Ans. D) All of the above
12. Density of structured vehicles can be Enhanced by adding
(A) Glycerin
(B) Polyethylene Glycols
(C) Suspending agents
(D) Both (a) and (b)
Ans. B) Polyethylene Glycols
13. In ideal suspension, the sedimentation Volume should be
(A) Zero
(B) Less than one
(C) Equal to One
(D) More than one
Ans. C) Equal to One
14. Synonym for cresol with soap solution is
(A) Lysol solution
(B) Lugol solution
(C) Phenol solution
(D) All of the above
Ans. A) Lysol solution
15. Compound Tragacanth powder is used when Vehicle is other than
(A) Water
(B) Ethanol
(C) Chloroform water
(D) Both A & C
Ans. D) Both A & C
16. The dilution of concentrated mouthwashes Is in the ratio of
(A) 1:5
(B) 1:2
(C) 1:1
(D) 5:1
Ans. A) 1:5
17. In the Avoirdupois calculation system, the Standard unit for weighing is
(A) Grain
(B) Pound
(C) Gram
(D) Ounce
Ans. B) Pound
18. The purpose of paraben in syrup is as
(A) Stabilizers
(B) Preservatives
(C) Buffers
(D) Thickeners
Ans. B) Preservatives
18. Which of the following dosage form is used to Deodorize bad breath
(A) Gargles
(B) Mouthwash
(C) Throat paint
(D) Tincture
Ans. B) Mouthwash
19. Which Type of solutions are instilled in the ear
(A) Oral solution
(B) Otic solution
(C) Ophthalmic solution
(D) All of them
Ans. B) Otic solution
20. Adsorbent such as light kaolin is incorporated In a solution of
(A) Incorporation of extracts
(B) Incompatible salts
(C) Incorporation of liquids
(D) Explosive mixtures
Ans. C) Incorporation of liquids
21. How many grams of boric acid is required to Make the prescription isotonic Atropine Sulphate 1.5% (e value Atropine = 0.13, Boric Acid 0.5) Boric acid q.s. Purified water up to 20 ml
(A) 0.141 gm
(B) 0.282 gm
(C) 0.423 gm
(D) None
Ans. B) 0.282 gm
22. Which of the following dosage form contains Glycerin as a base?
(A) Mouthwash
(B) Gargles
(C) Tincture
(D) Throat paint
Ans. D) Throat paint
23. One teaspoonful is equal to
(A) 4 ml
(B) 8 ml
(C) 3 ml
(D) 6 ml
Ans. A) 4 ml
24. How many mL of 2.50% (m/v) NaOH solution Would contain 3.50 g of NaOH
(A) 7
(B) 14
(C) 21
(D) 28
Ans. B) 14
25. The component of the solution which is present in a large quantity is known as
(A) Solvent
(B) Solute
(C) Continuous phase
(D) Both A and C
Ans. D) Both A and C
26. Liniments are prepared by taking one part of The requisite mother tincture and four parts of
(A) Glycerin
(B) Olive oil
(C) Yellow’s Beeswax
(D) Distilled water
Ans. B) Olive oil
27. Which of the following dosage form contains Sugar as the main component?
(A) Syrup
(B) Elixir
(C) Aromatic water
(D) Tincture
Ans. A) Syrup
28. The component of the solution which is Present in a small quantity is known as
(A) Solvent
(B) Solute
(C) Dispersed phase
(D) Both b & c
Ans. D) Both b & c
29. Which Type Of solutions are applied over the Skin surface
(A) Otic solution
(B) Oral solution
(C) Ophthalmic solution
(D) Topical Solution
Ans. D) Topical Solution
30. What is the label condition for eye drops
(A) Discard 24 hours after the first opening
(B) Discard 30 days after the first opening
(C) Discard 1 year after the first opening
(D) Discard 5 years after first opening
Ans. B) Discard 30 days after the first opening
31. Use of formulations made up of numerous Plants referred to as….
(A) Galenicals
(B) Parenteral
(C) Plant Vehicles
(D) Generics
Ans. A) Galenicals
32. Full form of “MDI”
(A) Metered Dose Inhaler
(B) Metered Dose Inhalation
(C) Metered drug ingestion
(D) Metered drug infusion
Ans. A) Metered Dose Inhaler
33. Rx means
(A) You take
(B) You give
(C) You bring
(D) All the above
Ans. A) You take
34. Primo mane meaning
(A) Every morning
(B) Early in the morning
(C) Equal morning
(D) Morning
Ans. B) Early in the morning
35. The meaning of the Latin term ‘submenus’ is
(A) To be taken
(B) You take
(C) To be used
(D) To be applied
Ans. A) To be taken
36. Capsules in which powders are enclosed are Made up of….
(A) Gelatine
(B) Rice flour
(C) Fructose
(D) Dextrose
Ans. A) Gelatine
37. Supplement to the first edition of IP was Published in …
(A) 1960
(B) 1975
(C) 1965
(D) 1968
Ans. B) 1975
38. Simple syrup is a saturated solution of….
(A) Sucrose
(B) Fructose
(C) Dextrose
(D) None of these
Ans. A) Sucrose
39. The meaning of ‘dolore urgente’ is
(A) When the pain is severe
(B) When the pain is absent
(C) Before meals
(D) None of the above
Ans. A) When the pain is severe
40. Douches are meant for application In….
(A) Buccal cavity
(B) Rectal cavity
(C) Vaginal cavity
(D) Nasal cavity
Ans. C) Vaginal cavity
41. Which type of glass is the material For multidose vials and ampoules?
(A) Neutral glass
(B) Soda lime-treated glass
(C) Amber color glass
(D) Silicone-treated glass
Ans. A) Neutral glass
42. Meaning of post cibos
(A) Before the meal
(B) After the meal
(C) Between meals
(D) Any time
Ans. B) After the meal
43. Pediatric doses are lesser than normal doses Because
(A) Of their lower body size
(B) Of their lesser body weight
(C) Their immunity system is not well developed
(D) Immature state of their hepatic and renal function
Ans. D) Immature state of their hepatic and renal function
44. The meaning of the word ‘Omni’ is
(A) Every
(B) Occasionally
(C) Suddenly
(D) Never
Ans. A) Every
45. All ointments are sterilized.
(A) True
(B) False
Ans. A) True
46. Cetrimide is available in which color?
(A) Black
(B) White
(C) Light green
(D) yellow
Ans. B) White
47. Cetrimide is soluble in water.
(A) True
(B) False
Ans. A) True
48. Cetrimide is insoluble in ….
(A) Water
(B) Warm water
(C) Ether
(D) None of these
Ans. C) Ether
49. Cetrimide cream is used as a
(A) Bactericide
(B) Antiseptic
(C) Skin irritant
(D) None of these
Ans. A) Bactericide
50. Cetrimide cream is packed in
(A) Narrow mouth container
(B) Plastic jars
(C) Collapsible tubes
(D) None of these
Ans. C) Collapsible tubes
51.’Mottling’ is the manufacturing defect associated with:
a. Capsules
c. Tablets
b. Ointments
d. Liniments
52. Which of the following is NOT a solid dosage form?
a. Tablet
b. Capsule
c. Cream
d. Powder
53. Which of the following statement regarding enteric coated tablet is NOT true?
a. Should not be crushed
b. Should not be taken with antacids
c. Should not be swallowed whole
d. None of the above
54. A paracetamol formulation consists of starch and magnesium stearate as additives. A person taking the above formulation developed a hypersensitivity reaction. It can be due to which of the following?
a. Paracetamol
b. Starch
c. Magnesium stearate
d. All of the above
55. In a patient who is experiencing vomiting, which of the following dosage forms of promethazine would be best?
a. Tablet
b. Syrup
c. Capsule
d. Suppositories
56. The blood of a reckless driver contains 0.1% alcohol. Express the concentration of alcohol in parts per million.
a. 100 ppm
b. 1000 ppm
c. 1 ppm
d. 250 ppm
57. If the adult dose is 60 mg and the age of the child is 4 years, according to Young’s rule the dose for the child will be:
a. 10 mg
b. 15 mg
c. 20 mg
d. 25 mg
58. Hospital formulary provides:
a. General information on drugs which are available in the country
b. Information for procuring, processing, dispensing, and administration of drugs in the hospital
c. Information on the latest adverse drug reactions and regulatory information on drugs
d. None of the above
59. The relative humidity in the operating area of capsule manufacturing is normally:
a. 60%
b. 50%
c. 40%
d. 20%
60. Complete separation of the tablet into two or more layers is called:
a. Capping
b. Lamination
c. Picking
d. Mottling
61. In an ideal suspension, the sedimentation volume should be:
a. Less than 1
b. Zero
c. Equal to 1
d. Between 0 to 1
62. Aspirin is preferably prepared by which method of tablet manufacturing:
a. Direct compression
b. Wet granulation
c. Dry granulation
d. Dry compression and dry granulation
63. Sucking tablets are:
a. For local adsorption
b. Designed to go into the bloodstream
c. Both of the above
d. None of the above
64. Rectal suppositories intended for adult use usually weigh approximately:
a. 1g
b. 2g
c. 4g
d. 4 g
65. Weight of rectal suppository for children is:
a. 1g
b. 2g
c. 5 g
d. None
66. Urethral suppositories are also called as:
a. Pessaries
b. Bougies
c. Both
d. None
67. Urethral suppositories have shapes:
a. Oviform shape
b. Torpedo shape
c. Pencil shape
d. All
68. Weight of urethral females respectively (in gram):
a. 4 & 2
b. 2 & 4
c. 4 & 6
d. 6 & 4
69. Suppositories are generally evaluated by:
a. Melting range test
b. Breaking test
c. Liquefaction
d. All the above
70. The pH of tears is about:
a. 6.0
b. 8.0
c. 7.4
d. 9.0
71. The appropriate pH range for opthalmic product is:
a. 2.0-3.0
b. 4.0- 6.0
c. 6.0-8.0
d. 8.0-10.0
72. Porosity of a porous powder is defined as:
a. Bulk volume/ Void volume
b. Void volume/ Bulk volume
c. Void volume/ True volume
d. True volume/ Bulk volume
73. A process of separation of molecules through the use of semipermeable membrane is known as:
a. Osmosis
b. Dialysis
c. Sieving
d. None of the above
74. Actuator is a part of aerosol package. It is used to :
a. Dispense the product in desired form
b. Prevent clogging of valve
c. Meter the accurate amount of dose to be dispensed
d. Provide proper attachment of valve to the container
75. Eye drops :
a. Is free from pyrogen
b. Should be sterile and free from foreign particles
c. Should be sterile and pyrogen free
d. All of the above
76. Levigation is defined as:
a. Settling of dispersed solids in suspension
b. Coalescence of dispersed globules in emulsion
c. Micronization of powder by grinding
d. Defect of tablet manufacturing
77. A batch of injectables consisting of 10,000 ampoules each containing 5 ml of the product, the number of ampoules is to be picked up randomly for sterility testing as per IP is:
a. 20 containers
b. 10 containers
c. 2% containers
d. 5%
78. In a friabillator, plastic chamber revolves at:
a. 100 rpm
b. 50 rpm
c. 25 rpm
d. 75 rpm
79. Which of the following equation is used to predict the stability of a drug product at room temperature from experiments at accelerated temperature?
a. Stoke’s equation
b. Michaelis-menten equation
c. Arrhenius equation
d. Young’s equation
80. Melting point of the suppository bases ranges from:
a. 50-60 °C
b. 37-40 °C
c. 20-30 °C
d. 45-50 ° C
81. Enteric coating material for tablet is:
a. Sodium carboxy methyl cellulose
b. Ethyl cellulose
c. HPMC
d. Polyvinyl acetate phthalate
82. Diffusivity of a solute is affected by:
b. Pressure
a. Temperature
c. Chemical nature
d. All of the above
83. The mesh size of USP disintegration apparatus is:
a. 2 mesh
b. 5 mesh
c. 10 mesh
d. 20 mesh
84. When one of a solute is soluble in nine parts of a solvent, then the solute is:
a. Very soluble
b. Soluble
c. Sparingly soluble
d. Freely soluble
85. During Norfloxacin tablet coating, your operator complains that there is an irregular distribution of color on the tablet, it is :
a. Capping
b. Chipping
c. Sticking
d. Mottling
86. Seal coating of ranitidine can be done with:
a. Shellac
b. Ethyl cellulose
c. Silicone
d. Any of the above
87. The friability of an uncoated tablet should be:
a. About 1 %
b. Less than 1%
c. More than 1%
d. Set by formulator
88. The content uniformity of a tablet (IP) is necessary when the tablet contents API :
a. Below 50 mg
b. Below 100 mg
c. Below 25 mg
d. Below 10 mg
89. How many milliliters of a 0.9 % aqueous solution can be made from 20 g of sodium chloride?
a. 2222
b. 222
c. 122
d. 100
90. Smallest size of capsule is:
a. 000
b. 1
c. 5
d. 4
91. The shell of capsule is made up of protein which is called:
a. Apalation
b. Gelatin
c. Celatin
d. None
92. Suppositories should be stored in:
a. Cold place
b. Cool place
c. Frozen conditions
d. Not specific
93. SOP is recognized abbreviation for:
a. Student Of Pharmacy
b. Staffing Of Pharmacy
c. Standard Operating Procedure
d. Surgical Operating Parameters
94. The abbreviation UNG means:
a. Eye drops
b. Ointment
c. If necessary
d. Universal dose
95. Sublingual tablets are supposed to take with:
a. Chewing properly.
b. Putting it under the tongue.
c. Putting at the buccal cavity
d. A glass of water
96. Which one of the following is NOT the purpose of coating?
a. Masking the taste
b. Increasing the elegance
c. Increasing efficacy
d. Improving stability
97. Which route of drug administration is most likely to lead to the first pass effect?
a. Sublingual
b. Oral
c. Transdermal
d. Intramuscular
98. Which one of the following is NOT true?
a. To prevent the drug from the influence of external environment
b. To mask bitter tastes
c. To increase friability
d. To make swallowing easier
99. Which of the following is NOT true about suspensions?
a. Some suspensions should contain an antimicrobial agent as a preservative
b. Particle settling could be avoided by using suspending agents
c. Tight containers are necessary to ensure the stability of the final product
d. The suspension should be viscous
100. Which of the following does NOT help to minimize the physical instability of suspensions after their formation?
a. Reducing the particle size of the powders
b. Using thickening agents
c. Using levigating agents
d. Using flavoring agents
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